educational program IN english “BIOLOGICAL ENGINEERING

THE SPECIALITY 5В070100 – BIOTECHNOLOGY

Academic degree: Bachelor of Technics and Technologies on specialty biotechnology

Name of modules

Discipline code

Names of disciplines (modules) and types of activities

Credit

ECTS

Lec/prac/Lab.

Sem.

1.     General Education

1.

GE

Compulsory Component

(21 credits)

MHK1102

The Modern History of Kazakhstan

3

5

2+1+0

1

K(R)L1106

Kazakh (Russian) Language

3

5

0+3+0

1

3

5

0+3+0

2

FL2108

Foreign Language

3

5

0+2+1

3

3

5

0+2+1

4

Ph2111

Philosophy

3

5

2+1+0

4

ICT1105

ICT Technologies

3

5

2+1+0

2

  1. BASIC DISCIPLINES

2.

BD

Compulsory Component

(20 credits)

PoK (R)L2201

Professionally-Oriented Kazakh (Russian)Language

2

4

0+2+0

3

PoFL2202

Professionally-Oriented Foreign Language

2

4

0+1+1

3

Phy1203

Physics

3

5

2+1+0

1

Mat1205

Mathematic

3

5

2+1+0

1

OB2206

Objects of biotechnology

3

5

2+0+1

1

IOC2207

Inorganic and Organic Chemistry

5

5

2+2+1

2

BCh2207

Biochemistry

2

4

1+0+1

3

3. Majors

3. M

Compulsory Component

(6 credits)

Phbio

Physiology for bioengineering

3

5

2+0+1

4

BBeng

Biophysics and bioengineering

3

5

2+0+1

5

4.Elective Course (6 credits GE; 40 credits BD; 6 credits M)

GE (6 credits)

GE

IBE

Introduction to Biological Engineering

3

5

2+0+1

4

GE

IB

Industrial biotechnology

3

5

2+0+1

5

BD (40 credits)

M (6 credits)

 

 

BD

MV

Microorganisms and viruses

3

5

2+0+1

2

BD

GMB

Genetic and Molecular biology

3

5

2+0+1

3

BD

CBT

Cell and tissue biology

3

5

2+0+1

1

BD

PhCh

Physical chemistry

3

5

2+0+1

2

BD

BBt

Basic of biotechnology

3

5

2+1+0

3

BD

Bst

Biostatistics

3

5

2+1+0

3

BD

BE

Biosystems engineering

3

5

2+1+0

4

BD

BMSF

Biomacromolecules: structure and functions

3

5

2+1+0

4

BD

BI

Biological imaging

3

5

2+0+1

4

BD

PDIB

Processes and devices in biotechnology

3

5

2+1+0

5

BD

EBt

Ecological biotechnology

3

5

2+0+1

5

BD

MBt

Medical biotechnology

3

5

2+1+0

5

BD

CBt

Cell biotechnology

3

5

2+1+0

6

M

SB

System biology

3

5

2+1+0

6

M

GE

Genetic engineering

3

5

2+1+0

6

BD

SW

Scientific writing

1

2

0+1+0

6

5. Individual educational trajectories (IET) (27 credits)

IET 1 Biomedical engineering

M

SABm

Structural Aspects of Biomaterials

3

5

2+1+0

5

M

DABm

Design and Analysis of Biomaterials

3

5

2+1+0

6

M

MCBe

Molecular and Cellular Bioengineering

3

5

2+1+0

6

M

BmOMBs

Biomedical Optical Microscopy and of biosensors

3

5

2+0+1

7

M

SCBe

Stem Cell Bioengineering

3

5

2+1+0

7

M

TE

Tissue Engineering

3

5

2+1+0

7

M

BiBm

Bioinformatics in Biomedicine

3

5

2+0+1

7

M

MI

Medical imaging

3

5

2+0+1

7

M

Bi

Bioinstrumentation

3

5

2+0+1

7

IET 2 Biochemical engineering

M

IBchE

Introduction to Biochemical Engineering

3

5

2+1+0

5

M

CMBchE

Computational Methods in biochemical Engineering

3

5

2+0+1

6

M

BchPMR

Biochemistry: Pathways, Mechanisms, and Regulation

3

5

2+0+1

6

M

PE

Protein Engineering

3

5

2+1+0

7

M

BGP

Basis of genomics and proteomics

3

5

2+0+1

7

M

EBP

Engineering of bioenergetic processes

3

5

2+1+0

7

M

EPDD

Engineering Principles for Drug Delivery

3

5

2+1+0

7

M

EE

Enzyme Engineering

3

5

2+0+1

7

M

AMBBE

Applied Molecular Biology for Biochemical Engineers 

3

5

2+1+0

7

IET 3 Environmental bioengineering

M

ESAE

Environmental Systems Analysis For Engineers

3

5

2+1+0

5

M

FEE

Fundamental of Environmental Engineering

3

5

2+1+0

6

M

WM

Waste Management

3

5

2+0+1

6

M

APE

Air Pollution Engineering

3

5

2+0+1

7

M

SBPE

Soil Biological processes and the Environmental

3

5

2+0+1

7

M

ER

Environmental Remediation

3

5

2+1+0

7

M

EDA

Environmental Data analysis

3

5

2+1+0

7

M

PhBt

Photobiotechnology

3

5

2+0+1

7

M

EM

Environmental Microbiology

3

5

2+0+1

7

IET 4

Nutritional engineering and safety

M

FChB

Food chemistry and biochemistry

3

5

2+1+0

5

M

NSt

Nutritional science and technology

3

5

2+1+0

6

M

TPRH

Technical processes related to heat and matter transport

3

5

2+1+0

6

M

FWS

Food and water safety

3

5

2+0+1

7

M

BFP

Baking and fermentation processes

3

5

2+0+1

7

M

MS

Microbiological sampling

3

5

2+0+1

7

M

FAQ

Food analysis and quality control

3

5

2+0+1

7

M

GLN

Genes, Lifestyle and Nutrition

3

5

2+1+0

7

M

DD

Diet and Disease

3

5

2+1+0

7

 

6. Interdisciplinary disciplines (2 credits)

 

M

IEI

Innovative entrepreneurship (by industry)

2

3

1+1+0

6

M

IR

Intellectual rights

2

3

1+1+0

6

M

E

Econometrics

2

3

1+1+0

6

M

MMBtI

Management and marketing in biotechnological industry

2

3

1+1+0

6

M

PP

Psychology and Pedagogy

2

3

1+1+0

6

M

L

Latin

2

3

1+1+0

6

M

CSLC

Culture of Speech and Language Communication

2

3

0+2+0

6

M

ALFC

Al-Farabi and Contemporaneity

2

3

1+1+0

6

Total theoretical training                                                                                                                                             129 credits

7. Practice

Professional practice (by types of practice)

Credit

ECTS

Week

Sem.

EP

Educational Practice

4

2

1

2

PdT

Pedagogy Training

3

2,5

2,5

8

PT

Practice Training

1+1

2,5

2,5

4,6

PrPT

Professional Practice Training

5

12,5

10

8

PdP

Pre-diploma Practice

2

7,5

5

8

8. Final Certification

8.1

Final examination

1

 

 

8

8.2

Writing and Presentation of Diploma Thesis

2

4,5

4

8

9. Additional Types of Learning

PhE

Physical Education

8

8

(0+0+2)

1,2,3,4

Total                                 156 credits

                   

 

LEARNING UNITS OF SUBJECTS

 

1. General Education

THE MODERN HISTORY OF KAZAKHSTAN

 

Learning Units:

 

1.                Kazakhstan on the way to Independence: the phase of development and nation-building ideas

1.1.         Socio-economic situation in Kazakhstan - preconditions struggle for independence.

1.2.         The origins of the national movement of the Kazakh people.

1.3.         The historical origins of the formation of the Soviet Kazakhstan: challenges indigenization.

1.4.         Formation of the Soviet totalitarian Kazakhstan: character, actions and consequences.

1.5.         The exploits and the loss of Kazakhstan in the fight against fascist aggression.

2.                The contradictions and consequences of Soviet reforms in Kazakhstan in the second half of the XX century.

2.1.         Apogee «cult of personality» and the influence of the «thaw» in the socio-political sphere.

2.2.         Socio-economic and spiritual «stagnation» Ecological problems of Kazakhstan.

2.3.         Attempts to "perestroika" Soviet Kazakhstan.

2.4.         State strategy and socio-economic development of independent Kazakhstan.

2.5.         Formation of government of the Republic of Kazakhstan.

2.6.         Kazakhstan model of economic development.

2.7.         Social reforms and changes in the field of education.

2.8.         Ethnodemographic processes and strengthening of interethnic consent.

3.                A democratic and spiritual renewal of independent Kazakhstan.

3.1.         Social and political prospects.

3.2.         The youth policy in the Republic of Kazakhstan and define the path of spiritual renewal.

3.3.         Policy formation of a new historical consciousness and outlook of the people of the Great Steppe.

4.                The value of the Leader of the nation program "People in the stream of history" for the formation of a new historical consciousness.

5.                The significance of the celebration of 550 anniversary of the Kazakh Khanate for the formation of a new social consciousness.

6.                «Mangilik El» - Kazakhstan national idea of the XXI century.

7.                Kazakhstan - a country recognized by the modern world.

 

KAZAKH (RUSSIAN) LANGUAGE

Learning Units:

 

1.                Introductory course: language and speech. The main functions of language.

1.1.         Language and its basic functions. Speech: types and forms of speech. General characteristics of the forms and types of speech.

1.2.         Text as the leading unit of verbal communication. The main features of the text. Methods of communication proposals in the text.

1.3.         Functional-semantic types of speech. Understanding the types of monologue speech.

1.4.         Functional styles of speech. General characteristics of functional speech styles.

1.5.         Conversational style. Art style. Journalistic style. Official-business style.

1.6.         Style and language features. The main genres of documentation. Preparation of documents: autobiography, resume, declarations, powers of attorney, receipts, reports and others.

1.7.         Scientific style and its features. Stylistic features of scientific style. Lexical and grammatical means of scientific style.

2.                Structural-semantic division of scientific text.

2.1.         Types of scientific information, incorporated in the text.

2.2.         Definition: general characteristics. Introduction of the term.

2.3.         Features more information text (summarizing, concretizing illustrating opening, the substitute).

2.4.         Communicative situation scientific field of communication.

3.                The culture of professional speech. Scientific discussion

3.1.         Oral scientific speech. Information genres: abstract, message, lecture, report. The structure of the oral monologue. Performing with elements dialogization: the question of the author - the answer to it, dialogized monologue - the interaction with the audience, the inclusion of students in the monologue.

3.2.         Convincing genres in scientific and journalistic style. Discussion. Dispute. Controversy. The objectives of the discussion of communication. Voice actions involved in the discussion dealing.

FOREIGN LANGUAGE

 

Learning Units:

 

1.            Higher education in Kazakhstan. The system of education in Great Britain and in the USA. My university. My future speciality.

2.            Environmental problems.

3.            Electricity. Non-traditional sources of energy.

4.            Electronics. Television.

5.            Computers.

6.            New technological achievements in new materials production.

7.            Made in Space. Transport for tomorrow.

8.            A New Era for Aircraft.

9.            Water transport.

10.       Technological and scientific achievements.

11.       Optical technology and laser application.

12.       Superconductivity.

13.       The International Space Station.

 

PHILOSOPHY

 

Learning Units:

 

1.                The subject of philosophy.

2.                Subject matter, purpose and function of philosophy.

3.                History of philosophy

4.                The philosophy of the ancient world.

5.                The philosophy of the Middle Ages of the East and the West

6.                Renaissance Philosophy

7.                The philosophy of the New Age

8.                The philosophy of the European Enlightenment of the XVIII century.

9.                Classical German Philosophy.

10.           The philosophy of the end of the eighteenth century - beginning of the XXI century.

11.           Kazakh philosophy.

12.           Basics of philosophical understanding of the world.

13.           Being as the central category of ontology.

14.           Development principle: dialectics and synergy.

15.           Possibilities and boundaries of knowledge. The specificity of scientific knowledge.

16.           Philosophy in the search and development.

17.           Philosophical anthropology.

18.           Social philosophy.

19.           Philosophical understanding of today's global challenges.

 

INFORMATION AND COMMUNICATION TECHNOLOGIES

Learning Units:

 

1.                The role of ICTs in key sectors of society. ICT Standards.

2.                Introduction into computer systems. Architecture of computer systems.

3.                Software. OS.

4.                Human-computer interaction.

5.                Database systems.

6.                Data analysis. Data management.

7.                Networks and Telecommunications.

8.                Cyber security.

9.                Internet technologies.

10.           Cloud and Mobile technologies.

11.           Multimedia technologies.

12.           Smart technology.

13.           E-technology. E-business. E-learning. E-government.

14.           Information technology in the professional sphere. Industrial ICT.

15.           ICT Development Prospects

 

 

2. Basic Disciplines

PROFESSIONALLY-ORIENTED KAZAKH (RUSSIAN) LANGUAGE

Learning Units:

 

1.    Introduction

1.1.         Introduction to the subject area on the professional Kazakh (Russian) language.

1.2.         Foundations for mastery of subject-language material.

1.3.         Basic categorical and conceptual apparatus in his professional Kazakh (Russian) language.

1.4.         Professional terminology in Kazakh (Russian) language.

1.5.         Feature content domain majoring in Kazakh (Russian) language.

2.    Simulation of random laws.

2.1.         Simulation of random numbers.

2.2.         Simulation of random events.

2.3.         Simulation of continuous random variables.

2.4.         Simulation of random vectors.

2.5.         Modeling of random processes and flow requirements.

2.6.         Identification of the random laws.

3.    Simulation models of information processes.

3.1.         Organization simulation.

3.2.         Simulation of queuing systems and Petri nets.

3.3.         Physical modeling.

3.4.         Simulation modeling of economic and organizational systems.

3.5.         Simulation modeling of management information systems.

 

 

PROFESSIONALLY-ORIENTED FOREIGN LANGUAGE

Learning Units:

 

1.                Introduction.

1.1.         Introduction to the subject area of specialty in the professional foreign language.

1.2.         Professional foreign language disciplinary phenomenon, serving all areas of human activity.

1.3.         Terminology, Lexicology of foreign languages. History of project management development.

2.                Project Life Cycle and Organization project.

2.1.         Summary of project management.

2.2.         Case classification projects.

2.3.         Project Life Cycle.

2.4.         Group management processes: initiation, planning, monitoring and management, execution, completion.

3.                Project Integration Management.

3.1.         The stages of project planning.

3.2.         Structural hierarchical decomposition of the work.

3.3.         Control the timing and cost of the project.

3.4.         Project Quality Management.

3.5.         Management of human resources and communications.

4.                Risk Management and Project Procurement.

4.1.         Identification of risks, risk response planning, project risk management.

4.2.         Project Procurement Management.

4.3.         Documentation, completion of the project.

4.4.         Trends in the development of project management theory.

4.5.         The use of special terminology, the vocabulary of the English language in the project management of information systems in science, technology and business.

 

PHYSICS

 

Learning Units:

 

1.                Mechanics

1.1.         Physics and measurement. Kinematics. Basic formulations and laws of body movement.  Motion in one and several dimensions. Distance, velocity, acceleration and their relations

1.2.         Circular motion and other applications of Newton’s Laws

2.                Dynamics

2.1.         Energy of a system. Conservation of energy

2.2.         Linear momentum and collisions. Rotation of a rigid object about a fixed axis. Angular momentum.

2.3.         Static equilibrium and elasticity. Universal gravitation.

2.4.         Oscillations and mechanical waves

2.5.         Oscillatory motion. Wave motion.

2.6.         Sound waves. Superposition and standing waves.

3.                Molecular physics and thermodynamics

3.1.         Temperature. The first law of thermodynamics.

3.2.         The kinetic theory of gases. Heat engines, entropy and the second law of thermodynamics.

4.                Electricity and magnetism

4.1.         Electric field. Gauss’s law. Electric potential.

4.2.         Capacitance and dielectrics. Current and resistance.

4.3.         Direct current circuits.

4.4.         Magnetic field. Sources of magnetic field.

4.5.         Faraday’s law. Inductance.

4.6.         Alternating current circuits. Electromagnetic waves.

5.                Optics

5.1.         Wave equation for the electromagnetic field

5.2.         Properties of light waves

5.3.         Diffraction of waves

6.                Quantum physics

6.1.         Thermal radiation. Experimental substantiation of basic ideas of quantum theory.

6.2.         Elements of quantum physics.

 

OBJECTS OF BIOTECHNOLOGY

 

Learning Units:

1. Cellular level of the organization of animals

2. Two-layer animals

3. Three-layer animals

 3. Characteristic of vertebra

4. Development of a vertebrate animal. Covers and a skeleton. Bodies of a metabolism and reproduction. Nervous system and sense organs.

5. Origin, systematization and distribution of vertebrate animals.

6. Features of a structure of a vegetative cell, tissue and plant’s organs.

7. Basic directions of morphological evolution of plants

8. Biological essence of reproduction and duplication, age and seasonal changes of plants.

9. Variety of flora, with features of a structure and duplication of various regular groups of the lowest and maximum plants

10. Bases of evolution of flora. Communications between plants, other alive organisms and an inhabitancy.

11. Systematization, evolution, phylogenezis, taxonomic categories and taxons.

12. Features of microorganisms.

13. Pro-and eukaryotic cells, and their differences.

14. Structures of the bacterial cell and Archaea.

15. Bacterial reproduction. Cellcycledifferentiation.

16. Ways ofrecombinationin bacteria.

17. Microbialcommunities. Biofilm.

18. Systematic, taxonomy, identification of microorganisms

19. General characteristic of viruses. Bacteriophages.

20. Cultivation andidentificationof viruses.

21. Modern scientific researches in the field of genetics and genomic.

22. Safety problems genetic modified industrial strains.

 

Inorganic and Organic Chemistry

Learning Units:

 

1. Chemical language and the structure of matter.

2. Composition and electronic structure of the atom

3. The electronic structure of the atom and the position of the element in the periodic table. Energy levels and sublevels.

4. Principle of construction. Complete and Ionic and covalent bond. Properties of atoms: ionization potential, electron affinity, electrocutivity.

5. Intermolecular connection and structure of matter

6. Classes of inorganic compounds. Classification and nomenclature of inorganic compounds.

7. Simple substances. Non-metals and metals. Properties: the difference between physical and chemical properties. Obtaining, applying

8. Oxides. Class definition. Nomenclature and classification.

9. Salt. Class definition. Nomenclature and classification.

10. Acids and alkali. Class definition. Nomenclature and classification.

11. Types of chemical reactions. The main types of chemical reactions in inorganic chemistry.

12. Solutions of non-electrolytes. Ways of concentration expressing.

13. Ion exchange processes.

14. Electrolytic dissociation.

15. Oxidation-reduction reactions.

Biochemistry

Learning Units:

1.     Introduction in Biochemistry.

2.     Proteins. Peculiarities of structure. Classification of proteins. Structural organization of protein.

3.     Enzymes. Structure, mechanism of enzyme action. Kinetics of enzymatic reaction.

4.     Carbohydrates. Classification. Biological significance. Properties of the main representatives.

5.     Lipids. Biological significance, classification. Characteristics of the main classes of lipids. Properties of lipids. Practical using of the main properties of lipids.

6.     Vitamins. Classification. Biological significance. Representatives.

7.     Nucleic acids. Peculiarities of structure. Biological significance. Structural organization of DNA. Types of RNA.

8.     Biosynthesis of Protein.  Transcription. Translation.

9.     Basics of metabolism.

10.                        Catabolism of proteins.  Glucogenic and ketogenic amino acids.

11.                        Catabolism of carbohydrates. Glycolysis. 

12.                        Krebs cycle. Oxidative phosphorylation.

13.                        Biosynthesis of glucose. Metabolism of lipids.

14.                        Oxidation of fatty acids.

15.                        Hormones. Classification. Representatives. Mechanisms of action.

 

 

 

 

 

3. Majors

 

PHYSIOLOGY FOR BIOENGINEERING

Learning Units:

1. Introduction to the physiology of human organ systems, including the cardiovascular, pulmonary, renal, and endocrine systems.

2. Review of basic principles of cellular physiology.

3. Membrane transport and electrophysiology.

4. Fundamental principles underlying human physiological processes and the methods used to monitor these processes.

5.  Composition and concentration of cellular and other body fluids.

6. Clinical conditions associated with dysfunction in specific physiological processes.

7. Role of medical devices and prostheses.

8. Processes of transfer molecules across membranes at the cellular, molecular, biophysical, and physiological levels.

9. Molecular machines that mediate membrane transport, generate electrical currents, or perform mechanical displacement.

10. Relationship between the molecular structures of membrane proteins and their individual functions.

11. The interactions among transport proteins in determining the physiological behaviors of cells and tissues.

12. Molecular motors and their mechanical relationship to cell function.

13. Use of engineering analysis and synthesis in problems in the life sciences and medicine.

14. Modeling of molecular physiological processes and design of artificial organs.

15. Systems theory and classical feed forward and feedback control in the context of physiological systems.

16. Application of classical control and systems theory to physiological systems. 

17. Scaling laws and the methods of continuum mechanics to biological transport phenomena over a range of length and time scales.

18. Physiological mechanisms of humans and representative model organisms.

19. Pathophysiology underlying common diseases.

20. Introduction to the study of quantitative physiology.

21. Physical, chemical and mathematical foundation of physiology.

22. Engineering strategies, techniques and tools used for understanding functions of living organisms.

23. Computer modeling used in the analysis of experimental data and in formulating mathematical descriptions of physiological events.

 

 

BIOPHYSICS AND BIOENGINEERING

Learning Units:

1.     Biophysics - the science about the physical and chemical processes in biological systems and about the mechanisms of their reactivity to physical environmental factors.

2.     Thermodynamics - the study of the process of exchange of energy, heat and matter in the organisms.Laws of thermodynamics.

3.     Biomechanics

4.     Autoregulation of the physical and chemical processes in the cells; biophysics of water structures. Biophysics and Fluid Flow

5.     Biophysics and Gas Transport

6.     Physics of Audition and Vision.  Wave processes in biological systems.

7.     Bioelectric potentials and bioelectrical phenomena. Role of ions in the development of biopotentials.

8.     Photobiological processes.

9.     Quantum biophysics. The action of ultraviolet radiation to proteins, nucleic acids and the organism.

10.         The main mechanisms of action of ionizing radiation in cellular and organism level.

11.          Methods for research the kinetics of complex systems.

12.          Biophysics of the sensory systems. Communication and speech.

13.         Instrumentation and signal processing in biology and medicine.

14.          Engineering-human interface. The application of fuzzy logic and neural network techniques in medicine.

15.          Mathematical modeling and its importance in biology. Physical and mathematical modelling, nerves, muscles.

 

4. ELECTIVE COURSES

INTRODUCTION TO BIOTECHNOLOGY

Learning Units:

1. Objects of biotechnology.

2. Basic concepts of biotechnology. Classification of biotechnological products.

3. Fundamentals of Industrial Biotechnology. Apparatus and nutrient media in biotechnology.

4. Classical and modern approaches to the selection of microorganisms

5. Classical and modern approaches to plant breeding

6. Classical and modern approaches in animal breeding

7. Genetic modification of microorganisms

8. The selection of the modified microorganisms. Genetic markers. Areas of achieving practical use of genetic engineering.

9. Transgenesis of plants and animals. Methods for introducing DNA into animal cells. Gene transfer using viruses.

10. Cell Engineering. Culturing the isolated cells and plant tissues. Requirements for the cultivation of biological objects culture in vitro. Types of tissue culture in plant cell engineering

11. Basic methods of animal cell engineering. Cultivation of animal cells.

12. Properties and sources of stem cells.

13. Protein engineering. Enzymes in biotechnology.

14. Environmental Biotechnology. Methods of environmental biotechnology.

15. Special biotechnology. Biologicals. Vaccines. Diagnosticums.

 

INDUSTRIAL BIOTECHNOLOGY

 

Learning Units:

1. Industrial development and production process

2. Downstream industrial biotechnology

3. Design of Fermentation Processes. How is quality control of raw materials performed.

Bioprocess Design, Computer-Aided.

4. Fermentation process of ethanol, including upstream, fermentation and downstream

4. 1-Butanol and acetone,  their  production, industrially used microorganisms

5. Acetic acid/vinegar, citric acid

6. Lactic acid, gluconic acid

7. Amino acids, economic considerations and production

8. Amino acids via enzymatic transformations

9. Amino acids, L-Glutamic acid, D,L-Methionine, L-Lysine and L-Threonine

10. Fungi as a producer in Industrial Biotechnology

11. Actinomycetes as a producer in Industrial Biotechnology

12. Antibiotics: industrial production

13. β-Lactam antibiotics: biosynthesis and manufacture

14. Amino acid and peptide antibiotics

15. Glycopeptide, polyether and nucleoside antibiotics

16. Tetracyclines, chinones, chinolones and other aromatic antibiotics

17. Antibiotics: industrial production, resistance

18. Scaledown of Biopharmacuetical Purification Operations

19. Protein Adsorption, Expanded Bed

20. Protein Aggregation and Precipitation, Measurement and Control

 

MICROORGANISMS AND VIRUSES

 

Learning Units:

 

1.  Introduction. A subject and microbiology problems. Features of microorganisms.

2. Pro-and eukaryotic cells, and their differences.

3.  Surface structures of the bacterial cell.

4. Internal structures of the bacterial cell.

5. Bacterial reproduction.

6. Cellcycledifferentiation.

7. Microbialcommunities. Biofilm.

8. Ways ofrecombinationin bacteria.

9. Systematic of microorganisms

10.Taxonomyofmicroorganisms.

11. Identification ofmicroorganisms.

12. Archaea.

13. General characteristic of viruses.

14. Bacteriophages.

15. Cultivation andidentificationof viruses.

 

GENETIC AND MOLECULAR BIOLOGY

Learning Units:

 

1. Structure and forms of DNA and RNA;

2. Methods of its isolation;

3. Genome organization;

4. DNA replication;

5. Structure of the gene. Transcription;

6. Features of genetic code;

7. Translation;

8. Regulation oа gene expression on the level of transcription and translation;

9. Mutations. Spontaneous and induced mutagenesis;

10. Mechanisms of DNA reparation. Approaches and methods of recombinant DNA production and cloning

 

CELL AND TISSUE BIOLOGY

 

Learning Units:

 

1.     Different types of cells, especially eukaryotic cells; functional and structural similarities and dissimilarities between them.

2.     Structure and function of important biomolecules, organelles and other cellular components.

3.     Cellular organization and specialization

4.     Structure and function of important biomolecules, organelles and other cellular components.

5.     Cell signalling, cytoskeleton proteins, intracellular transports, cell cycle regulation, and cellular differentiation

6.     The biochemical processes that underlie cellular function

7.     The components of biological membranes, including the various types of membrane proteins.

8.     Cell cycle and control mechanisms

9.     Differentiation of Specialized Cells Stem cell differentiation; Blood cell formation; Fibroblasts and their differentiation; Cellular basis of immunity; Differentiation of cancerous cells and role of proto-oncogenes

10.                       Programmed cell death and the immune system cells

11.                       Function of particular organelles, including cell membranes, intracellular compartments and the cytoskeleton, and the relevance of these structures on processes like cell signaling and mitosis.

12.                       Morpho-functional classification of tissues;

13.                       Structure and function of various tissues;

14.                       Biomaterials for tissue engineering

15.                       Methods for tissue analysis, such as histological preparation techniques, histochemistry and immunofluorescence

 

 

 

PHYSICAL CHEMISTRY

 

Learning Units:

 

     1. Physical chemistry as a natural science, its subject and objectives. Stages of development

2. Subject, objectives and significance of thermodynamics. Basic concepts and values. Systems. Thermodynamic system

     3. Thermal effects of chemical reactions. Thermochemistry.

      4. Dependence of the thermal effects of chemical reactions on the temperature

      5. Entropy. Insufficiency of the first law of thermodynamics to characterize systems

      6. Determination of the kinetics as a part of physical chemistry. Basic concepts and values (speed, molecularity, order, rate constant).

      7. Reactions of Ist and IInd orders. Determination of the reaction order. Effect of temperature on the rate. Arrhenius equation.

      8. Total thermodynamic condition. Thermodynamic derivation of the law of mass action

      9. Phase equilibria and its criteria. Gibbs phase rule

     10. Diagrams of systems with simple eutectic

     11. Three-component system.

     12. Aqueous solutions of electrolytes

     13. Equilibrium in electrolyte solutions.

     14. Colloidal solutions

 

BASIC OF BIOTECHNOLOGY

Learning Units:

1. History of development of Biotechnology.

2. Biotech varieties

3. Basic direction of biotechnology.

4. Microorganisms, Plant and Animal cell culture as object of the Biotechnology

5. Methodological principles of cultivation

6. Methodological principles of fermentation

7. Technologies of isolating, cleaning and producing a new biotechnological products

8. Plant cell culture as subject of the Biotechnology.

9. Main directions and issues of modern biotechnology of animals.

10. Technologies of isolating, cleaning and producing a new biotechnological products

 

 

BIOSTATISTICS

 

Learning Units:

 

1, 2. Concept of statistics, its significance, scope.

3, 4. Variability and methods of its study.

5, 6. Basic parameters characterizing the population. Statistical analysis of quantitative traits.

7, 8. The theory of representation.

9, 10. Statistical analysis of qualitative features.

11, 12. Correlation analysis.

13, 14, 15. Analysis of variability.

 

BIOSYSTEMS ENGINEERING

 

Learning units:

 

1. Environmental Engineering.

2. Irrigation and Water Resources Engineering.

3. Power and Machinery Engineering.

4. Process and Food Engineering.

5. Structures Engineering.

6. Model-based design of bioprocesses (up-stream processing, bioreactor operation and downstream processing).

7. Design of cellular systems.

8. Integration of recombinant technology and process design.

9. Bioinformatics and process systems engineering.

10. Sustainable production of biorefinery compounds.

11. Rational manipulation of biosystems.

12. Biofuels production.

13. Nutraceuticals and bioactive molecules.

14. Biomaterials.

15. Ecologically-sound food, energycrop and feedstock production systems

16. Low-impact development strategies (bioretention basins, rainwater harvesting, and bioswales for stormwater retention, treatment, and management).

 

BIOMACROMOLECULES: STRUCTURE AND FUNCTIONS

Learning Units:

 

1.     Basic macromolecular structure: protein, carbohydrates, DNA, RNA, lipids.

2.Biological structure databases. 

3.The folding process and structural background to the dynamics of macromolecules

4.     Structure analysis and classification of proteins in structural families. 
Macromolecular functions. 
Relation between sequence, structure and function.

5.     Methods for the determination of macromolecules structure and interaction. .
Computer modelling of secondary- and tertiary structure of proteins and nucleic acid based on Binding specificity, catalysis and cooperativity in enzymes and receptors.

6.     Introduction to computational modelling of ligand binding, protein folding and enzyme catalysis.

7.     Enzyme/receptor-based drugs-rational drug design.

8.     Different types of interactions that exist between biomolecules.

 

BIOLOGICAL IMAGING

 

Learning units:

 

1.  Introduction to Biological Imaging.

2. Optical Imaging.

3. Overview of Microscopy.

4. Tissue Optics.

5.  Optical Imaging (Fluorescence).

6. Optical contrast agents.

7. Introduction to Magnetic Resonance Imaging.

8. Structural and Functional MR Imaging.

9. Nuclear Medicine Imaging.

10. Overview of PET/SPECT.

11.  Contrast Agents for PET/SPECT.

12. Oncologic Imaging (pre-clinical).

13. Overview of Image Quantification.

14. Microfluidics in radiopharmaceutical development.

15. Applications of Imaging: Oncologic Imaging-Clinical, Cardiovascular Imaging with PET/SPECT, Targeted radiotherapies, Microscopy applications, Clinical Lung Imaging, Neuroimaging, Functional MRI.

 

PROCESSES AND DEVICES IN BIOTECHNOLOGY

Learning Units:

 

1. Introduction to the course, the basics of biotech manufacturing.

2. Mode of Operation of Fermentation Processes

3. Media for Industrial Fermentations

4.  Bioreactor Configurations . Components of a Fermenter

5. Bioreactor Design Features

6. Types of Fermenters. 

7. Energy Input in Bioreactors

8. Characteristics of Cells in Culture

9. Shear Effects in Culture

10. Lyophilization: Growing with Biotechnology.

11. Integrated lyophilization: balance between cooling and drying, freezing, primary drying, secondary drying, supercooling, pressure control and heat transfer during lyophilization

12. Downstream Processing aspects

13. Methods of Cell Lysis.  Mechanical Methods. Nonmechanical Methods

14. Steps Involved in the Process of Cell Fractionation

15. Centrifugation. Centrifuges, Types of Rotors, Safety Aspects of Centrifugation

16. Filtration

17. Disintegration of Cells. Homogenization. Methods of Homogenization.

18. Refolding of Inclusion Bodies, Methods of Refolding

19. Separation of Soluble Particles. Purification of the Separated Components

20. Solubilization and Refolding of Proteins

ECOLOGICAL BIOTECHNOLOGY

 

Learning Units:

 

1. The use of microorganisms and microbial biotechnology for the improvement of the biosphere (objectives, methods and principles). The ecological role of microorganisms in the biosphere.

2. Genetically modified organisms and their role in environmental biotechnology.

3. Main sources of environmental pollution. Types of environmental pollutants.

4. Biological factors of natural environments pollution. Pollution by industrial strains of microorganisms and genetically modified organisms.

5. Microorganisms like bioindicators of environmental pollution.

6. Microbial processes of organic pollutants : biodegradation, cometabolizm, polymerization, accumulation.

7. Remediation of contaminated soils. Bioremediation. Advantages and disadvantages of bioremediation.

8. Microbial preparations improving soil environment.

9. Bioremediation of oil-contaminated soil and water. Bioremediation of soil contaminated with polycyclic aromatic hydrocarbons.

10. The problem of storage and processing of waste. Composting.

11. Solid waste. Biodegradation of solid waste in landfills. Microbial treatment of industrial waste. The elimination of toxic and hazardous substances.

12. Biological treatment of wastewater. Biological methods of cleaning.

13. Microbiological fundamentals of bioenergy materials. Preparation of alcohols (methanol, ethanol, butanol, butanediol).

14. Bioconversion of cellulolytic materials.

15. Obtaining biogas from farm waste.

 

MEDICAL BIOTECHNOLOGY

 

Learning Units:

 

1.General description of medical biotechnology. Basics directions of medical biotechnology.

1.     Antibiotics: characteristics, classification, propertiesMethods in production of antibiotics.

2.     Hormones: characteristics, classification, properties, biological functions Biotechnological methods of producing hormones.

3.     Vitamins: characteristics, classification, properties, biological functions, methods of producing vitamins.

4.     Immunology. Basic principles of immunology.

5.     Immunobiotechnology. Monoclonal antibodies. Hybridoma technology. Target-therapy.

6.     Vaccines as a drugs for immunization.

7.     Vaccines biotechnology

8.     Cytokines, types, function in the human organism. Methods of obtain cytokines.

9.     Immune diagnostic analysis in medicine. IEA, ELISA, RIA, IChA, test-system for diagnostics.

10.                       Gene therapy in gene correction.

11.                       Regenerative medicine. Stem cells biotechnology.

12.                       Cell therapy in tissue/organ transplantation.

13.                        Regenerative medicine. Stem cells biotechnology.

14.                         Use of biochips in diagnostics of diseases

CELL BIOTECHNOLOGY

 

Learning Units:

 

1. Objectives and purposes of cell biotechnology . Biological systems used in cell biotechnology .

2. Genetic engineering and design of new organisms-producers

3. Basic concepts of genetic engineering: cloning, transformation, vector.

4. Methods of producing genes. Chemical-enzymatic synthesis of genes.

5. Directed mutagenesis. General properties of vectors. Vectors for genetic cloning - special aspects of their molecular organization

6. Animal cell biotechnology as an object. Cultivation of eukaryotic cells

In vitro. Application.

7. The technology of obtaining and cultivating animal cell lines

     8. Advantages and limitations of tissue culture method.

9. Transgenic cell lines. Transfection (Methods for introducing exogenous DNA into mammalian cells).

10. Methods of creating chimeras.

11. Hybridization of animal cells.

12. Methods of producing transgenic animals. Knockout animals.

13. The plant cell as the object of biotechnology.

14. Cell plant biotechnology. Directions. Cultivation of individual cells. Totipotency.

15. Main directions of plant cell engineering. Use of transgenic plants

 

SYSTEM BIOLOGY

 

Learning Units:

 

1.     Subcellular and cellular systems

2.     Dynamic biosystems modeling and computer simulation methods for studying biological/biomedical processes and systems at multiple levels of organization

3.     Methods for the analysis of metabolic, gene-regulatory, and large-scale networks

4.     Structural modeling methods applied to life sciences problems at molecular, cellular (biochemical pathways/networks), organ, and organismic levels.

5.     Both theory- and data-driven modeling, with focus on translating biomodeling goals and data into mathematics models and implementing them for simulation and analysis.

6.     Graph theoretic analysis of biological networks

7.     The techniques of System  Biology and computational simulation

8.   limitations of current systems biology methods and needs for future development

9.     Methods and results in the general field of systems biology.

 

GENETIC ENGINEERING

Learning Units:

 

1. History of the developmentof genetic engineeringGeneral principles and methodsof genetic engineering

2, 3. Methodsfor isolating and identifyinggenes.Methods of preparationfor cloninggenes

4. Vector systemin prokaryotesExpression vectorsandcloning vectors

5, 6. Functionalfeatures of the structureof the genetic apparatusof prokaryotesComparativeanalysis of the organizationof the geneticinformationandpro-andeukaryotic.

7. Creation of industrial producing strains by genetic engineering. Directed mutagenesis of the DNA molecules in vitro

8. Genetically engineered yeast system. Cloning of genes into cells of S. cerevisiae.

9. Expression vector system S. cerevisiae

10. Secretionof foreign proteinsfrom cellsS.cerevisiaeProductionof foreign proteinsinS.cerevisiae

11. Insect virusesas vectors ofexpression offoreign genes

12. Genetic transformation ofmammalian cells.Introductionof DNAinto mammalian cells

13. Transgenic animalsin basic researchBiotechnological applicationof transgenic animals

14. Vector systems based on animal viruses.

15. Transgenicplants with newbiotechnologicalproperties.Transgenic plantsin agriculture.

 

SCIENTIFIC WRITING

 

Learning Units:

 

1-2. Introduction. Tasks and philosophical backgrounds of scientific reasoning

3-4. Literature search. Citing principles. Drafting an abstract. Current state-of art in abstract composing

5-6. Scientific paper as one of the main grounds for the development of scientific reasoning skills. Preparing the paper. Review writing. Evaluation of experimental or review articles. Tactics to the editorials.

Drafting a grant proposal

scientific research

9-10. Online learning and commercialization of

11. Rithorics as powerful tool for recruiting students, teams and finding adherents

12. Designing a poster

13. Perspectives and constraints of scientific development

 

 

 

 

 

 

 

 

 

INDIVIDUAL EDUCATIONAL TRAJECTORIES (IET)

 

IET 1 BIOMEDICAL ENGINEERING

 

STRUCTURAL ASPECTS OF BIOMATERIALS

 

Learning Units:

1. Principles of materials science as it relates to the use of materials in the body.

2. Characterization of biomaterials.

3. Natural and synthetic load-bearing biomaterials for clinical applications.

4. Properties of biomedical materials used as implants.

5. Properties of biomedical materials used as prostheses and orthosis.

6.  Properties of biomedical materials used as medical devices in contact with the human body.

7. Biocompatibility of biomaterials and host response to structural implants.

8. The mechanisms of cell interactions with extracellular matrix components as well as cell/tissue responses to implant materials

9. Receptor-ligand communication, methods of identification and quantification, and pathways involved for cell to material stress response.

10. Blood composition and blood-material interactions, responses of the inflammatory and immune systems to biomaterials, the process of wound healing, protein structure and interactions with material surfaces

11. Quantitative treatment of biomechanical issues and constitutive relationships of tissues for structural function.

12. Material selection for load bearing applications including reconstructive surgery, orthopedics, dentistry, and cardiology.

13. Mechanical design for longevity including topics of fatigue, wear, and fracture

14. Case studies that examine failures of devices

15. Ethics, toxicology, economic and business implications of biomedical materials.

 

 

DESIGN AND ANALYSIS OF BIOMATERIALS

 

Learning Units:

 

1. Introduction to the fundamental science of natural and synthetic biomaterials used for repairing human tissues and organs.

2. Different types of biomaterials used for medical devices

3. Certain metal alloys as implantable materials.

4. Ceramics as implantable materials.

5. Polymers systems as implantable materials.  Modified polymers to enhance biomedical applications.

6. Introduction to tissue engineering. Tissue-engineered systems.

7. Incorporation living cells in order to provide a true biological and mechanical match for the living tissue.

8. Artificial/biological composites used as implantable materials.

9. Materials and nano-fabrication methods with applications to biomedical engineering.

10.Crystal structures, phase diagrams, and properties of materials.

11. Mathematical analysis towards rational design of biomaterials

12. Physiochemical properties of materials that are considered important to meet the criteria specified for the implant and device applications (e.g. strength, modulus, fatigue and corrosion resistance, conductivity)

13. Safety requirements for biomaterials enough to withstand the repeated forces of a lifetime (nontoxic, non-carcinogenic, chemically inert, stable, and mechanically strong etc.)

14.  Practical aspects associated with biomaterials such as sterilization, packaging, evaluating device failures as well as regulatory guidelines will

15. Regulatory guidelines and standards governing biomaterials

 

MOLECULAR AND CELLULAR BIOENGINEERING

 

Learning Units:

 

1. Biotechnology in the cellular and molecular level.

2. The structure and function of the cell from an engineering perspective.

3. Cellular structure, signal transduction, cell adhesions, cytoskeleton.

4. The structure and function of DNA, the flow of genetic information in a cell, genetic mechanisms.

5. Introduction to the realm of molecular bioengineering with a focus on genetic

engineering.

6. The methodology involved in recombinant DNA technology and its application in society in terms of cloning and genetic modification of plants and animals (transgenics).

7. The methodology involved in recombinant DNA technology and its application in society in terms of biotechnology (pharmaceutics, genomics).

8. The methodology involved in recombinant DNA technology and its application in society in terms of bioprocessing (production and process engineering focusing on the production of genetically engineered products.

9. The methodology involved in recombinant DNA technology and its application in society in terms of gene therapy.

10. Engineering principles (kinetics, transport, mechanics, thermodynamics, electrochemical gradient) for biological engineering.

11. Methods to disrupt, enhance or mimic in vivo cellular function in biomedical applications.

12. Specific engineering principles that are applied to gene therapy.

13. Problems involving structure and function of molecules and cells in areas such as drug design and delivery.

14. Production factors such as time, rate, cost, efficiency, safety, and desired

product quality.

15. Societal issues involving ethical and moral considerations, consequences of regulation, as well as risks and benefits of molecular and cellular bioengineering.

 

BIOMEDICAL OPTICAL MICROSCOPY AND OF BIOSENSORS

 

Learning Units:

 

1. The basic principles of optical microscopy and imaging techniques commonly used in biomedical research.

2. The advantages and limitations of the various types of optical microscopy

3.  The appropriate microscopy technique to solve specific biomedical problems.

4. The fundamental principles of modern and classical optics and their applications for biomedical research

5. The cutting-edge research in the area of optics and lasers in medicine and biology

6. The fundamental principles of biophotonics and their applications to address critical issues in the frontier of biomedical science and technology.

7. The fundamentals of light interactions with molecules, cells, and tissues, optical imaging.

8. Flow cytometry and photodynamic therapy

9. Laser tweezers and laser surgery.

10. Comprehensive introduction to the basic features of biosensors. Optical, electrochemical, acoustic, piezoelectric, and nanobiosensors.

11.Types of most common biological agents (e.g. chromophores, fluorescence dyes) and the ways in which they can be connected to a variety of transducers to create complete biosensors for biomedical applications.

12. Optical biosensors and systems (e.g. fluorescence spectroscopy, microscopy). 13. Fiberoptically-based biosensing techniques.

14.  New technologies such as molecular beacons, Q-dots, bioMEMs. 

15. Confocal microscopy and multiphoton microscopy.

 

STEM CELL BIOENGINEERING

 

Learning Units:

 

1. The interface of stem cell biology and bioengineering

2. Cell and molecular biotechnology concepts

3. Embryonic and adult stem cell biology fundamentals

4. Stem cells and their differentiation

5. Analysis of biomolecular therapies to regulate stem cell function

6. Design of biomolecular therapies to regulate stem cell function

7. Production of biomolecular therapies to regulate stem cell function

8. Generation of biomimetic to creation cell biotechnological products, including stem cell derivatives

9. Generation of bioreactor environments to generate cell biotechnological products, including stem cell derivatives

10. Cell-Biomaterials Interactions.The cascade of events in vivo immediately after implantation, cell responses to physical and chemical modifications of biomaterial surfaces.

11. Chemical-physical forces controlling interactions at the biomolecule/cell/water/biomaterial interface

12. Cell signaling and feedback mechanisms between the extracellular matrix or implant surfaces and cell surface expression of biomolecules

13. Examples of responses of specific cell types to implant properties including, mesenchymal stem cells, osteoblasts, osteoclasts, chondrocytes and neural cells

14. Bacterial biofilm infections at implant surfaces in vivo.

15. Implant design and tissue engineering applications.

 

TISSUE ENGINEERING

 

Learning Units:

 

1.                Developmental biology (nature's tissue engineering)

2.                Mechanisms of cel-cell interactions

3.                Mechanisms of cell-matrix interactions

4.                Biomaterial formulation

5.                Characterization of biomaterial properties

6.                Evaluation of cell interactions with biomaterials

7.                Biomechanics characterization, modeling, and properties of regenerating tissues

8.                Principles of designing an engineered tissue

9.                Basic principles and techniques in animal cell culture.

10.           Theoretical and practical aspects of culturing and sub-culturing established cell lines

11.            Various tissue engineered components including blood vessels, bone, cartilage

12.            Tissue engineered components including pancreas, liver and skin.

13.            Analysis of dialysis systems for kidney replacement, artificial hearts and heart assist devices, cardiac pacemakers, sensory organ assist and replacement devices, and artificial liver and pancreas devices.

14.            Considers manufacturing parameters such as time, rate, cost, efficiency

15.            Safety and desired product quality as well as regulatory issues.

 

BIOINFORMATICS IN BIOMEDICINE

Learning Units:

 

1.     Bioinformatics and Molecular Medicine. Components of molecular medicine.

2.     Molecular Biotechnology and Molecular Medicine

3.     Information technology of analysis the nucleotide sequences of the genes. Information technology of analysis the amino acid sequences of proteins

4.     The role of bioinformatics in diagnosis of diseases

5.     Methods for detection of hereditary diseases

6.     Computational methods for detecting metabolic diseases

7.     Molecular diagnosis of diseases

8.     The use of molecular markers in biomedicine.

9.     Structural and functional diversity of the organization of eukaryotic genomes.

10.                       Setting the functional properties of DNA features.

11.                       Comparative characteristics of the genomes at the structural and functional organization.

12.                       Analysis of completely sequenced genomes of eukaryotes.

13.                       Molecular cloning method.

14.                       Bioinformatics and pharmacogenomics.

15.                       The role of bioinformatics in the modification of eukaryotic organisms

 

 

 

 

MEDICAL IMAGING

 

Learning Units:

 

1. Imaging as an essential component of the modern physician’s arsenal of diagnostics. Design image reconstruction algorithms.

2. Development of devices and systems to image the human body to diagnose diseases.

3. Application of mathematical analysis in medical imaging.

4. Physical phenomena such as sound, radiation, magnetism, and light with high-speed electronic data processing, analysis, and display to generate an image.

5. Design and testing of hardware and software for acquiring and analyzing biological signals.

6. Radiographic and fluoroscopic techniques.

7. Data processing of the CAT scan.

8. Principles of computed tomography.

9. MRI (magnetic resonance imaging) system.

10. Ultrasound imaging system.

11. Relations between imaging technologies and the design of target specific probes.

12. Optical and x-ray imaging systems, and signal and image analysis techniques.

13. Physics of nuclear medicine 

14. Emission computed tomography system, including PET and SPECT.

15. Different types of biotelemetry systems and patient monitoring

16. Introduction to MATLAB

17. Electrical safety.

 

BIOINSTRUMENTATION

 

Learning Units:

 

1. Instrumentation systems, operational modes, measurement characteristics.

2. Fundamental principles of bioinstrumentation used in clinical and research measurements: principles of transducer operation, amplifiers and signal processing, recording and display.

3. Electronics and measurement techniques for the development of devices used in the diagnosis and treatment of disease.

4. Design and fabrication of medical devices.

5. Analysis of physiologic function using principles of mechanics, mass- or heat-transfer, or fluid dynamics.

6. Design of musculoskeletal, cardiovascular, and other prosthetic devices.

7. Development of treatment methods such has thermal ablation systems.

8. EKG, EMG and EEG systems.

9. Unique challenges in the design of probes of each modality: specificity, delivery, and amplification strategies.

10. Design and assembly of bioinstrumentation of sensors. Basic sensors in biomedical engineering, biological signal measurement, conditioning, digitizing, and analysis.

11. Advanced applications of LabVIEW, a graphics programming tool for virtual instrumentation.

12. Virtual instrumentation for laboratory research and prototyping medical devices.

13. Electronic devices such as heart monitors, intensive care equipment, cardiac pacemakers for diagnosis and treatment of disease.

14.Origin of biopotentials. Biopotential electrodes.

15. Methods of engineering and computational mechanics to understand the function of bones, joints, and muscles, and for the design of artificial joint replacements.

16.Distribution of electrical power, safety in bioinstrumentation, electrical hazards.

 

 

 

 

 

 

 

IET 2 BIOCHEMICAL ENGINEERING 

 

INTRODUCTION TO BIOCHEMICAL ENGINEERING

Learning Units:

 

1.     Introduction to biochemical and microbiological applications to commercial and engineering processes.

2.     Biochemical processes

3.     Application of engineering principles to analyze, design, and develop processes using biocatalysts

4.     Analysis, and interpretation for biokinetic, thermodynamic, and stoichiometric calculations used in biochemical engineering

5.     The biological factors that are important in the design, operation, performance, and/or monitoring of a biological process

6.     Kinetic calculations to biochemical reactor design and operation

7.     Bioethics issues and ethical aspects of biological engineering

8.     Metabolic pathways important for biochemical engineers

9.     Contributions of biochemical engineering to global society

 

COMPUTATIONAL METHODS IN BIOCHEMICAL ENGINEERING

 

Learning Units:

 

1.     Linear and nonlinear algebraic equations, root problems, numerical optimization, finite difference methods, interpolation,

2.     Linear and nonlinear regression analysis, differentiation and integration, and ordinary differential equations (initial value and boundary value problems).

3.     Introduction to MATLAB.

4.     Introducing the theory of variable and matrices.

5.     Basic operations and plotting.

6.     Introduction to process modeling and simulation.

7.     Examples of chemical, Biochemical and environmental engineering problems arising in fluid mechanics.

8.     Thermodynamics, heat and mass transfer, separation processes.

9.     Reaction engineering, process dynamics, and transport phenomena.

10.                        Introducing advanced visualizations commands in MATLAB.

 

BIOCHEMISTRY: PATHWAYS, MECHANISMS, AND REGULATION

 

Learning Units:

 

1.     Introduction to Metabolism: Logic and pathways.

2.     Enzyme mechanism & activity

3.     Metabolic homeostasis

4.     Integrating anabolic/catabolic pathways

5.     Energy flux with nutrition/nutrient intake of essential and non-essential molecules

6.     Regulatory control through allosteric, transcriptional/translational, and post-translational mechanisms

7.     The basics of advanced biochemical metabolic pathways.

8.     Regulation of metabolism

9.     The regulation and storage of sugar in the cell.

10.                       Techniques for quantitating metabolism

11.                       Photosynthesis and the Light Reactions.

12.                       Carbon assimilation and the Dark Reactions.

13.                       Amino acid and nucleotide biosynthesis.

 

PROTEIN ENGINEERING

 

Learning Units:

 

1.     Structural and functional organization of protein molecules;

2.     Methods of modification of natural proteins;

3.      Isolation of genes from host organisms, cloning, preparation of recombinant proteins, host organisms, protein expression and protein purification.

4.     methods and techniques used to engineer and design proteins with novel properties for scientific, medical, industrial and agricultural

5.     Random and site-directed mutations of proteins using genetic methods

6.     Design of proteins in vitro, in silico, and de novo.

7.     Applications of protein engineering in biotechnology, medicine, pharmacy, food products and ecology.

8.     Combinatorial methods using biological and chemical approaches

 

BASIS OF GENOMICS AND PROTEOMICS

 

Learning Units:

 

1.     Structural and functional bases of proteomics

2.     Principles and methods of analysis of the proteome

3.     Databases in Proteomics

4.     Simulation of physical and chemical properties and functions of proteins

5.     Prospects for the study of proteomes of plants and animals

6.     SAGE and Differential display proteomics, Protein-protein interactions, Yeast two hybrid system.

7.     Human Proteome and treatment of socially significant diseases

8.     Protein chips.

9.     Introduction Structural organization of genome in Prokaryotes and Eukaryotes

10.                       DNA sequencing-principles and translation to large scale projects

11.                       Genome sequencing projects Microbes, plants and animals

12.                       Comparative genomics, Identification and classification using molecular markers-16S rRNA typing/sequencing, ESTs and SNPs

13.                        Pharmacogenetics and drug development

 

 

ENGINEERING OF BIOENERGETIC PROCESSES

 

Learning Units:

 

1.     Introduction to bioenergetics.

2.     Coupling of an exergonic to an endergonic reaction.

3.     Transfer of free energy from an exergonic to an endergonic reaction via a high-energy intermediate compound.

4.     Redox cycle of the biosphere. 

5.     The diversity of membrane proteins. Mechanisms of molecular biological membrane transport.

6.     Classes of bioenergetic processes: fermentation, photosynthesis and respiration.

7.     Substrate-level phosphorylation. High-energy phosphate compounds.

8.     Role of ATP/ADP cycle in transfer of high-energy phosphate. Energy charge. 

9.     Bioenergy economics. Bioenergy and environment. Overview of process engineering for bioenergy.

10.                     Ionofores. Endogenous uncouplers.

11.                    ATP formation under anaerobic conditions and in anaerobic microorganisms.

12.                     Respiratory chain, production of ATP.

13.                    Electron transport and oxidative phosphorylation. Components of respiratory chain.

14.                    The mechanism of chemiosmotic coupling of electron transport and oxidative phosphorylation. Renewable energy technologies.

15.                    Biogas production by microbial processes;

16.                    Anerobic digestion, microbial hydrogen production.

17.                    Biofuels from microalgea and seaweeds; Technologies, economic analysis, environmental impact.

18.                    Biodiesel from vegetable oils; Transesterification process, glycerol utilization. Bioethanol.

 

 

 

 

 

 

ENGINEERING PRINCIPLES FOR DRUG DELIVERY

 

Learning Units:

 

1.     Topics include: drug delivery mechanisms (passive, targeted); 

2.     Therapeutic modalities and mechanisms of action;

3.     Engineering principles of controlled release and quantitative understanding of drug transport (diffusion, convection);

4.     Effects of electrostatics, macromolecular conformation,

5.     Molecular dynamics on interfacial interactions;

6.     Thermodynamic principles of self-assembly;

7.     Chemical and physical characteristics of delivery molecules and assemblies (polymer based, lipid based);

8.     Significance of biodistributions and pharmacokinetic models;

9.     Toxicity issues and immune responses.

 

 

ENZYME ENGINEERING

 

Learning Units:

1. Introduction to enzyme technology

2. Enzyme Catalysis and Inhibition

3. Carbohydrate structure and enzymology

4. Lignin structure & enzymology

5. Other substrates & enzymes

6. Protein structure and stability

7. Sources of industrial enzymes (natural & recombinant)

8. Large-scale industrial enzyme production

9. Screening for new and improved enzymes

10. Methods in enzyme engineering

11. Metabolic engineering

12. Enzymes in plant fiber-based industries

13. Enzymes in fuel production

14. Enzymes in food production

15. Clinical uses of Enzymes

 

APPLIED MOLECULAR BIOLOGY FOR BIOCHEMICAL ENGINEERS 

 

Learning Units:

 

1.     DNA structure, replication, central dogma, genetic code, transcription,

2.     RNA structure, translation,

3.     tRNA and ribosome structure,

4.     Polypeptides, proteins,

5.     Plasmids, chromosomes, genomes,

6.     Cultivation of mammalian, yeast and bacterial cells, human cells as therapeutics,

7.     Gene syntax in mammalian, yeast and bacterial cells,

8.     Transfection of human cells,

9.     Transformation of yeast and bacterial cells,

10.                        Synthetic biology,

11.                        DNA analytics

 

 

 

 

 

 

 

IET 3 ENVIRONMENTAL BIOENGINEERING

 

ENVIRONMENTAL SYSTEMS ANALYSIS FOR ENGINEERS

 

Learning Units:

 

1. Basis of the systems theory and systems analysis. Systems and patterns of their formation and development

2. Elements of systems analysis in ecology and environmental protection

3. Ecology of biosphere. Material, energy and information processes in ecosystems

4. Environmental laws related to energy flows biosphere

5. Elements of bioenergy ecosystems

6. Information in plant communities

7. Information fields of animals

8. Models and simulation in ecology

9. Factors, operating in ecosystems. Interference in ecosystems

10. Space of environmental factors

11. Cybernetic nature and ecosystem's stability

12. Biological regulation of geochemical environment

13. Diagnostics and effective monitoring of the environment

14. Geoinformation mapping. Distance sounding of the earth

15. Using of distance and GIS technologies for the purpose of rapid and dynamic mapping of natural resources and environmental monitoring

 

 

FUNDAMENTAL OF ENVIRONMENTAL ENGINEERING

 

Learning Units:

 

1. Analysis of problems related to the environmental impact of the most environmentally troubled industries

2. Structure of industrial and technological systems, their hierarchy and functioning

3. Stock and energy subsystems of technology production systems

4. Classification, causes and mechanism of production waste

5. Diagnostic and effective monitoring of the environment

6. Effects of industrial pollution on the environment and human

7. Standart base and the quality of the control environment

8. Ekological rationing. The method of expert evaluations

9. Ekological-economic assessment and analysis of the socio-cultural areas

10. Sistems of environmental control of production in industry

11. Tehnology and technical means of protection of atmospheric air from dust and gas emissions

12. Production stocks and water treatment systems

13. The value of analytical techniques and methods in the assessment of natural objects.

14. Organization of laboratory and field studies.

15. Contemporary global analytical methods, equipment and instruments using in  assess the scope of the state.

 

 

WASTE MANAGEMENT

 

Learning Units:

 

1. Wastes from the production and consumption as a source of pollution

2. Properties of waste production and consumption. The calculation of the danger class for the environment and for human

3. Solid-waste. Processes and installations of solid waste recycling.

4. Processes and devices for the treatment of sewage sludge.

5. Gas cleaning. Gas cleaning methods.

6. State regulation of the activities of production and consumption waste

7. Certification of danger waste. Rationing and licensing for the management of danger waste.

8. State accounting and reporting in the field of waste management

9. Control in the field of waste management (public, industrial, public)

10. Economic in waste management regulation

11. Waste Technology.

12. Management of waste production and consumption

13. The procedure for taking into account waste management. Inventory of sources of waste generation. Placement of waste

14. Waste transportation

15. The use, dumping, disposal of waste

 

 

AIR POLLUTION ENGINEERING

 

Learning Units:

1. The role of the atmosphere in the development of animate and inanimate nature.

2. Air pollution. Types of pollution. Sources of pollution.

3. Basic and specific pollutants in the ambient air.

4. Danger classes of pollutants. Air pollution index (API).

5. The conditions that determine the level of contamination.

6. Physical and chemical processes in the atmosphere. Smog, the kinds of smog.

7. Complex indicators characterizing the possibility of air pollution - air pollution potential (APP), diffusing capacity of the atmosphere, the self-cleaning capacity of the atmosphere.

8. The background pollution levels. The extent of contamination.

9. Rationing air quality. Sanitary-hygienic standards of air quality - maximum permissible concentration of pollutants (MPC), their types and purpose.

10. Production and economic standards of air quality: maximum permissible emissions (MPE), a time-approved emissions (TAE).

11. Non-traditional alternative energy sources (wind, solar energy) as a promising way to solve environmental problems.

12. Creating a closed technological cycles, waste-free and low-waste technologies.

13. Devices for the treatment of emissions. Methods for cleaning emissions. Dispersion of dust and gas emissions.

14. Sanitary protection zones. Architectural and planning activities.

15. Legal basis for air protection and realization of citizens' constitutional right to a healthy environment and reliable information about its condition.

 

 

SOIL BIOLOGICAL PROCESSES AND THE ENVIRONMENTAL

 

Learning Units:

 

1. Soil-forming rocks. Influence of the breed on the particle size and mineralogical composition of the soil, on the soil speed. Living organisms as a factor of soil formation.

2. Climate as a factor of soil formation. Relief as a soil-forming factor. Direct and indirect effects of topography on soil formation.

3. Soil organic matter. The role of humus in the processes of soil formation and soil fertility.

4. The water in the soil. Categories of soil moisture. The soil solution. Water regime of the soil and his types.

5. The soil air. The ratio between the solid, liquid and gaseous phases of the soil.

6. Physical properties of soil density, porosity, water permeability, moisture capacity, water-lifting and water-holding capacity.

7. Soil horizons. Types of soil horizons. The soil profile. The distribution of substances in the profile. Types of structure of the soil profile.

8. The essence of soil-forming processes. Simple, basic and general (total) soil processes.

9. Soil formation processes.

10. Laws of soil cover formation. Classification of soils.

11. Environmental sustainability of soil and soil cover: assessment, opportunities, outlook.

12. Soil erosion. Soil dehumidification. Secondary salinization.

13. Soil pollution due to incorrect using of fertilizers. Pollution of soils with heavy metals, oil and oil products. Radioactive contamination of soils.

14. Reclamation of anthropogenic soils and landscapes.

15. Simulation of anthropogenic impacts optimization on the soil and soil cover.

 

ENVIRONMENTAL REMEDIATION

 

Learning Units:

 

1. Bioremediation. Types and remediation factors.

2. Characteristics of the main types of pollution of the biosphere. The biological activity of xenobiotics.

3. The natural bioremediation. Engineering bioremediation ex situ: bioreactors, biofilters, composting, reclamation.

4. Biotransformation of organic xenobiotics.

5. Opportunities for improved remediation technologies of contaminated soils through the use of biodestructures

6. Purification of water and sediment from the organic and nutrient pollution

7. Microorganisms-destructors for bioremediation processes.

8. Microbial populations aerobic and anaerobic bioremediation processes.

9. Bioremediation of contaminated soils

10. Phytoremediation of anthropogenically disturbed waters

11. Removal of heavy metals from the natural environment with the solid phase, disadvantages and prospects removal methods.

12. Accumulation of xenobiotics, factors determining the degree of accumulation.

13. Ways to improve systems of aerobic and anaerobic wastewater treatment.

14. Features biostimulation of indigenous cultures of microorganisms. Bioaugmentation, advantages of the process and prospects for the use of specialized products.

15. Factors contributing to the effectiveness of bioremediation. Factors limiting the bioremediation process.

 

 

ENVIRONMENTAL DATA ANALYSIS

 

Learning Units:

 

1. One-dimensional statistical models as a tool to process and analyze the information in geoecology and environmental management.

2. General and sample. Basic requirements for the total sample (mass, uniformity, randomness, independence).

3. Main geoecological problems of one-dimensional statistical models - estimation of  objects parameters and statistical hypothesis testing.

4. The density of the probability distribution function, discrete and continuous distributions.

5. Build and histogram analysis. Average values in geoecology and their use for various tasks.

6. The accuracy of the estimates. Probability distribution function of the random variables.

7. Statistical hypothesis and the criteria for their verification.

8. Correlation, factor analysis and regression. The concept of correlation.

9. Characteristics of the correlation for distress and form. The study of correlations tabular, graphical and analytical methods.

10. The sequence of computing operations, examples. The significance of the correlation coefficient.

11. The use of correlation for comparison of samples.

12. The concept of multiple correlation. Rank correlation.

13. The method of interpreting correlations (correlation matrices).

14. Cluster analysis as a geoenvironmental data research tool.

15. The concept of principal component analysis and factor analysis.

 

PHOTOBIOTECHNOLOGY

 

Learning Units:

 

1. The role of phototrophic microorganisms in photobiotechnology development.

2. The mass cultivation of phototrophic microorganisms.

3. Types of systems for the cultivation of phototrophic microalgae - open and closed systems.

4. Types of photobioreactors (flat, tubular, depth, etc.). Their use in different countries.

5. Using of mikroalgae biomass for dietary supplements in medicine and in agriculture.

6. The use of microalgae in different sectors of human activity - in agriculture (food additives), food industry (food additives), in the field of environmental protection.

7. Nitrogen fixated phototrophic microorganisms and their importance in soil fertility.

8. The role of phototrophic microorganisms in bioindication and bioremediation.

9. Modern installations (photoreactors) for the cultivation of phototrophic microorganisms.

10.Basic areas of phototrophic microorganisms modern biotechnology.

11. The use of phototrophic microalgae as renewable raw material for receiving of energy.

12. The search for new, advanced technologies to produce biomass of microalgae (as raw material, and in order to clean the air) in bioenergy.

 

ENVIRONMENTAL MICROBIOLOGY

 

Learning Units:

 

1. The microorganisms metabolisms, its features. Distribution of microorganisms and their metabolic characteristics defined by ecological niches habitats.

2. Communities of microorganisms. The structure of the communities. The relationship between community members.

3. Methods of isolating microorganisms from natural sources and the study of the structure of microbial communities.

4. Cultivated and uncultivated microorganisms from natural sources. The biochemical characteristics of microorganisms.

5. Methods of microbial identification based on biochemical parameters of the composition (lipids, phospholipids).

6. Molecular biological methods for studying microorganisms and microbial communities.

7. The role of microorganisms as the pollution of the environment indicators. Genetically modified microorganisms as a new factor in the impact on the environment.

8. Genetic exchange in microbial communities. The horizontal transfer of genetic information.

9. The self-cleaning of the process environment due to the activity of microorganisms.

10.Basic anthropogenic pollutants in the environment: oil products, pesticides, waste, waste chemical production.

11. Biotechnology as an alternative to chemical technology. Variants of using biotechnological approaches in the products production.

12. Antibiotics, their application, limitations. Production of antibiotics. Manufacture of pharmaceuticals. Microbiological synthesis, biotransformation, enzyme catalysis.

13. The use of biocatalysts as a way to build a waste-free technologies.

14. Methods of construction of industrial microorganisms strains.

15. Construction metaboloms, metabolic engineering.

IET 4 «Nutritional engineering and safety»

 

FOOD CHEMISTRY AND BIOCHEMISTRY

 

Learning Units:

1.     Water in Foods

2.     Freeze-and thaw phenomena

3.     Lipids in Foods

4.     Melting points, cloud points, viscosity, plasticity of lipids

5.     Proteins in Foods (Acid /base chemistry)

6.     Proteins in Foods (protein solubility)

7.     Carbohydrates in Foods

8.     Kinetics of Food Processes

9.     Acid-catalyzed Sucrose Inversion

10.                        Modeling Reaction Kinetics

 

Nutritional science and technology

Learning Units:

1.     Elementary statistics, averages, probability distributions, hypothesis testing, data correlation, linear regression. Introduction to spread sheets, manipulating data sets using spread sheets, plotting graphs, correlating data and interpreting relevant statistics

2.     Composition of biological materials and its effect on physical properties

3.     Units and dimensions and dimensionless groups

4.     Introduction to physical concepts such as velocity, acceleration, momentum, force, pressure, work, energy and power

5.     Circular motion

6.     Mass and energy balances, energy conversion processes

7.     Size shape, density, porosity, specific heat, latent heat and, enthalpy

8.     Introduction to rheological properties

9.     Fluid statics and hydrodynamics 

10.                       Interfacial properties and optical, electromagnetic and electrical properties.

 

TECHNICAL PROCESSES RELATED TO HEAT AND MATTER TRANSPORT

Learning Units:

1.      Stages from ingredients to final product

2.     Factors determining the selection of appropriate processing methods (e.g. type of freezer, separation by filtration or centrifugation, etc.)

3.     Functional constituents (e.g. selection of gelling agents, emulsifiers etc.)

4.     Methods for sourcing equipment and ingredients

5.     Writing of product specifications and ingredients specifications

6.     Determining Heat Transfer: mechanisms and processes

7.     Heat exchangers, heat treatment processes and kinetics

8.     Evaporation

9.     Dehydration, including mass transfer considerations

10.                       Care and storage of food during transportation

11.                       Changes of food during transportation

12.                       Packages

13.                       Electromagnetic and novel processes

14.                       Cleaning and hygiene

15.                        Raw material properties in relation to processing Heat Transfer: mechanisms and processes

16.                       Hazard Analysis and Critical Control Point (HACCP) and Good Manufacturing Practice (GMP) protocols

 

Food and water safety

 

Learning Units:

1.     Concept of quality

2.     Specifications and safety auditing

3.     Quality management documentation

4.     Quality management systems (including ISO 9001, 9004 and 22000; BRC Global Standard; GFSI)

5.     Hazard analysis 

6.     Toxicological testing methods

7.     Legislation: An introduction to national food control including a study of the legal framework in the Kazakhstan and international approaches

8.     Microbiological Sampling

9.     Microbiological standards

10.            Regulation of Nutrition Labeling and Dietary Supplements

11.            Requirement for drinking water safety

12.            Present and future issues for the water industry

13.            Multiple barrier system for protecting water quality

14.            Statistical methods in food quality assurance

 

 

Baking and fermentation processes

Learning units:

1.     Ecophysiology and metabolism of sourdough yeasts

2.     Ecophysiology and metabolism of lactic acid bacteria.

3.     Drivers to establish the sourdough microbiota

4.     Sensory, shelf life and nutritional features of the baked goods, as determined through the leavening agent (baker’s yeast or sourdough)

5.     Protocols for making industrial and artisanal baked goods

6.     Protocols for making gluten-free products

 

 

Microbiological sampling

Learning Units:

1.     Aspects of microbial physiology

2.     Food borne pathogens and important considerations for food production

3.     The detection and control of microbial hazards

4.     Food borne illnesses that require microbial multiplication in foods and do not require multiplication in foods

5.     Modern assays for detecting the microbial content of foods

6.     Molecular methods and differentiation techniques (which are used to monitor both microbial hazards and functional cultures, such as starter cultures and probiotics)

7.     The metabolic pathways during food fermentation

8.     Lactic acid and ethanol fermentation

9.     The main characteristics of lactic acid bacteria and yeast

10.                        The production of various fermented foods (dairy, meat-based and vegetable based)

11.                        The application of fermentation for the production of food ingredients.

Food analysis and quality control

 

Learning Units:

1.                Chromatography, gel filtration, ion-exchange, HPLC, GC-MS, chiral separations and applications in food analysis

2.                Analytical quality control and sample preparation

3.                UV-visible spectrophotometry, principles and applications

4.                IR, NIR, FTIR spectroscopy

5.                NMR and Raman spectroscopy; spectrofluorimetry  principles and applications 

6.                Electrophoresis, non-dissociating and dissociating PAGE, iso-electric focusing; applications

7.                Rheology and food texture

8.                Organolepsis: sensory analysis

9.                Protein analysis - proximate analysis of meat products

10.           Sugars – determination of sugars in different jams

11.           Physical and chemical properties of starches

12.           Physical and chemical properties of fats and oils

13.           Analysis of caffeine by HPLC - statistical evaluation and precision

 

 

Genes, Lifestyle and Nutrition

 

Learning Units:

Introduction to gene structure, regulation, and chronic diseases

1.     Introduction to gene structure and regulation and chronic diseases

2.     Epigenetics

3.     Genetic epidemiology of metabolic traits

4.     Gene discovery methods in genetic epidemiology

5.     Gene-lifestyle interactions – diet and physical activity

6.     Diet-genotype interactions- complex traits such as diabetes, obesity and CVDs

7.     Diet genotype interactions- cancer

8.     Fetal origin of adult disease

9.     Personalized Nutrition

 

 

Diet and Disease

Learning Units:

1.     Scientific basis of the dietetics profession

2.     Governance of dietetics practice, such as scope of dietetics practice and the code of ethics

3.      The principles of Medical Nutrition Therapy

4.     The practice of the nutrition care process

5.     Principles and methods of assessment, diagnosis, identification and implementation of interventions

6.     Strategies for monitoring and evaluation

7.     The physical and biological science foundation of the dietetics profession

 

 

 

 

 

 

INTERDISCIPLINARY DISCIPLINES

 

INNOVATIVE ENTREPRENEURSHIP (BY INDUSTRY)

 

Learning Units:

 

1.        The general provisions of the innovative entrepreneurship.

2.        Introduction to the theory of innovations.

3.        Innovation process and its stages.

4.        The basic agents of innovative activity.

5.        Preparation of an innovative project.

6.        Business planning of innovation project.

7.        Marketing of Innovation.

8.        Managing Innovation in small business.

9.        Financing innovation.

10.   Examination of innovative projects.

11.   The risks of innovation entrepreneurship.

12.   Business ethics and corporate culture.

13.   State innovation policy.

14.  Legal aspects of innovation.

 

INTELLECTUAL RIGHTS

Learning Units:

 

1.       The Introduction to Intellectual Law.

2.       International regulation of Intellectual.

3.       Activity Licensing Agreements.

4.       The general concept of copyright.

5.       Subjects and objects of copyright.

6.       Copyright protect.

7.       Allied rights.

8.       The general concept of Patent Law.

9.       Subjects and objects of Patent Law.

10.  Patent, types, protection Topologies of Integrated Circuits.

11.  Selection achievements.

12.  Trade marks.

13.  Commercial names.

14.  The Right to Protect Confidential Information.

15.  Illegal Use.

 

ECONOMETRICS

 

Learning Units:

 

1.      Introduction to Econometrics.

2.      Statistical hypothesis testing.

3.      The statistical properties of estimators.

4.      Model Estimation using Ordinary Least squares.

5.      Multiple Linear Regression Model.

6.      The Gauss-Markov Theorem.

7.      Standard error of the regression.

8.      Testing, hypotheses relating to the regression coefficients.

9.      Coefficient of determination. The Chow test.

10.    Specification of regression variables. Correlation.

11.    Nonlinear econometric models.

12.    Multicollinearity.

13.    Heteroscedasticity.

14.    Autocorrelation.

15.    Detection of Autocorrelation.

 

Management and marketing in biotechnological industry

 

Learning Units:

1. Requirements for marketers in biotechnological industry.

2. Theoretical foundations of marketing.. Definition of marketing.

3. Evolution of marketing development.

4. The main types of marketing. Marketing concepts and their evolution.

5. Needs and market - the basis of marketing activities.

6. The concept of the market. Elements of the market.

7. Definition of demand. Types of demand.

8. System of marketing research.

9. Methods of analyzing information about the market.

10. Forecasting the commodity market.

11. Segmentation of the market and product development

12. Pricing and price policy.

13. Management, planning and control of marketing

14. Demand formation and sales promotion

15. International marketing.

 

Psychology and Pedagogy

Learning Units:

1. The system of formation and development of the child as a subject of activity

2. Integrative open developing system of continuing pedagogical education

3. The training and educational association based on innovative methods

4. Scientific and scientifically methodical projects

5. Formation of professional competence of the future pedagogue-psychologist

6. Preparation of experts for system of modern high school education

7. Modernization of system of higher education as social institute in the Republic of Kazakhstan

8. Moral education of students based on electronic cultural programs

9. The theory and practice of formation of independence among students of secondary school age

10. Pedagogy of correction of difficulties in communicating of preschool children in the family

11. Formation a culture of communication of preschool children

12. The Psychology of adolescent deviant behavior.

 

 

LATIN

Learning Units:

 

1.                History of the Latin language and its role in shaping the international terminology.

2.                Phonetics. Pronunciation of consonants, vowels and letter combinations.

3.                Rules setting accents.

4.                Nomen sustantivum. Grammatical categories of Latin nouns.

5.                Nomen adjectivum. Declinatio 1, 2

6.                Nomen adjectivum. Declinatio 3. The dictionary form of nouns of the 3rd declension. Determination of the basis.

7.                Nomen adjectivum. Location and function of an adjective in a sentence. Degrees of comparison of adjectives. Consistent and inconsistent definition.

8.                Nomen adjectivum. Gradus comparatives et superlativus.

9.                Pronomena. Pronouns (personal and reflexive, possessive and demonstrative).

10.           Nomena numeralia. Numerals (quantitative, ordinal, separation, adverbial). Declination and use numerals.

11.           Verbum. Grammatical categories of Latin verbs.

12.           Infekta system. Paradigms conjugation.

13.           The syntax of a simple sentence. Driving parsing of a simple sentence.

14.           Word formation. Basic Latin and Greek prefixes and suffixes of adjectives and nouns.

15.           General questions of terminology.

 

CULTURE OF SPEECH AND LANGUAGE COMMUNICATION

Learning Units:

 

1.                Language as a means of communication. Text as highest communicative unit. Structural and semantic analysis of text in specialty.

1.1.         Language and speech. Functional speech styles. Scientific style of speech. Language features of scientific style.

1.2.         It offers a minimum communicative unit. Logical-semantic relations in sentence. The proposed model. The formulation of question to semantic center of proposal and its basic properties.

1.3.         Text as highest communicative unit (text attributes, connectivity). Functional-semantic types of speech: description, narration, reasoning. The types of links in text.

1.4.         Structural and semantic articulation of text. Subject text. Communicative task of text.

1.5.         Methods of information in text.

1.6.         The progression of text. This new information, and text.

2.                Compression of text. Secondary scientific text.

2.1.         Compression of text. Methods and compression mold. The main and additional text information.

2.2.         Text Plan specialty. Types plan. Synopsis text.

2.3.         Abstract and abstract as the main genres of scientific speech in educational and professional spheres. Patent description as a basis for creation of a secondary text of any genre: modes of administration of initial information to the secondary text. Language means of the introduction of the initial information to the secondary text.

2.4.         Annotation. Annotations structure. Standard language means design annotations.

2.5.         Abstract. Types of abstracts.

2.6.         Standard design means abstract.

AL-FARABI AND CONTEMPORANEITY

 

Learning Units:

 

1.                Al-Farabi’s life and work.

2.                Study of consciousness.  Al-Farabi’s concept of human cognitive ability.

3.                Al-Farabi’s theory of emanation and the role of mind.

4.                Impact of Aristotelian and Stoic logic on formation of Al-Farabian logic.

5.                Al-Farabi and the European Renaissance

6.                The Primary Reason problem in the Al-Farabi’s ontology

7.                Interaction between “necessarily existing” and “potentially existing” in the Al-Farabi’s ontology

8.                Naturphilosophy and contemporaneity.

9.                The place of natural science among classification of sciences by Al-Farabi

10.           Interaction between natural science and study of God in the Al-Farabi’s doctrine

11.           Philosophy of art. The main ideas in Al-Farabi’s “Great Book on Music”

12.           The canons and genres defined by Al-Farabi in poetics.

13.           Al-Farabi’s outlook on religion.

14.           Content of Al-Farabi’s “On Religion” treatise

15.           Al-Farabi’s social-ethic teaching.

16.           Al-Farabi on the role of religion in social needs.

17.           City as the most perfect form of society.

18.           The role of virtue in achievement of happiness.

19.           “Al-Farabi university smart city” is a sample of Al-Farabi’s virtues city. The role of cities in social development Essence and activity of contemporary smart-city.

 

 

 

 

 

 

Новости

СТУДЕНТЫ НА ПРЕМЬЕРЕ ТРАГЕДИИ ЛЬВА ТОЛСТОГО «АННА КАРЕНИНА» НА КАЗАХСКОМ ЯЗЫКЕ

В рамках реализации проектов «Айналаңды нұрландыр» и «Духовное возрождение» 25 ноября 2018 года студенты 2-го курса специальности «5В070100-Биотехнология» посетили Казахский государственный академический театр драмы им. М.Ауэзова, где посмотрели премьеру и обсудили показ на казахском языке трагедии Льва Толстого «Анна Каренина».  

Организаторы: Мелдебекова А.А., Нармуратова М.Х., Турашева С.К., Ерназарова Г.И.

 

«МИКРОБИОЛОГИЧЕСКИЙ КВЕСТ, НАУЧНЫЙ БАТЛ»

Уважаемые преподаватели и студенты факультета Биологии и биотехнологии!

27 ноября в 9.00 в 519 аудитории на кафедре биотехнологии состоится «МИКРОБИОЛОГИЧЕСКИЙ КВЕСТ, НАУЧНЫЙ БАТЛ» среди студентов 2 курса специальности биотехнология.  

Организаторы преподаватели кафедры биотехнологии: Игнатова Л.В., Бержанова Р.Ж., Мукашева Т.Д., Савицкая И.С., Омирбекова А.А., Карпенюк Т.А., Гончарова А.В.

 

23 Января 2018 года кафедра биотехнологии факультета биологии и биотехнологии совместно с научными сотрудниками института биологии и биотехнологии растений НЦБ МОН РК провели профориентационную работу «Моя будущая профессия» для студентов 2 курса специальности «5В070100 - Биотехнология». Цель мероприятия: ознакомление с возможностями построения профессиональной карьеры в исследовательских институтах РК; развитие мотивации достижения успеха в профессиональной деятельности.